Exogenous surfactant in the late respiratory phase of COVID-19

Will exogenous surfactant treat respiratory distress syndrome?

The Impact of Late Secondary Hyperparathyroidism on Mortality in COVID-19 Patients: A Longitudinal Study

Background: Adverse effects of high parathormone hormone (PTH) in critical illness have been described in some studies.  Objective: The relationship between high PTH levels with mortality in hospitalized patients with COVID-19 was evaluated in the present study. Methods: A total of 123 patients were included in the study. The patients were evaluated in phase 1 (on admission) and phase 2 (days...

Sinoorbital Mucormycosis as a Late Complications of Covid-19

Introduction: Mucormycosis is a rare, progressive, and dangerous fungal infection with a high mortality rate. There have been several reports of increased mucormycosis rate during the COVID-19 pandemic. Case Presentation: Here, we report a 69 years old men of sinoorbital mucormycosis as a late complication of COVID-19. Endoscopic sinus surgery was performed underwent general anesthesia and all...

Exogenous surfactant in acute respiratory distress syndrome: more is better.

Pulmonary surfactant is a complex of highly active phospholipids and proteins that cover the alveolar epithelial surface of the lungs [1]. Surfactant is synthesized in the alveolar type-II cells, stored in the lamellar bodies, and secreted to the alveolar space where it undergoes complex changes [2]. The composition of lung surfactant in humans is very constant, although it may change in diseas...

Neonatal Respiratory Distress Syndrome: 40 years of Exogenous Surfactant

On August 9th , 1963, Patrick Bouvier Kennedy, the son of USA President John F. Kennedy and Jacqueline Bouvier, died after 39 hours of life, being born 5 1⁄2 weeks premature. This was not a so severe prematurity, but anyhow he was affected by HMD, and at that time only oxygen was available for neonates with respiratory failure. Of course such death gave a great prompt to the research in this fi...